Professor Marek Lubusky, MD, PhD, MHAProfessor Marek Lubusky, MD, PhD, MHA

Pětroš M., Ľubušký M., Šimetka O., Procházka M. Pregnant women alloimmunization of non-RhD erythrocyte antigens: review artice

ABSTRACT

Objective: The aim of this review is to give comprehensive summary on alloimmunisation of non-RhD erythrocyte antibodies. Design: Review. Setting: Department of Obstetrics and Gynecology, University Hospital Ostrava, Department of Obstetrics and Gynecology, University Hospital Olomouc. Subject and method: Based on literature analysis using database search engines PubMed, Google Scholar, Ovid and Proquest in field of non-RhD erytrocyte antibodies, there has been summarized up-to-date knowledge on irregular antibodies. Conclusion: Pregnant women alloimmunisation of non-RhD erythrocyte antigens gather importance in conjunction with relative increase of their occurence. Profylaxis is not possible. Although these erythrocyte antigens are able to induce antibody responce in mother and result in subsequent hemolytic disease of fetus and newborn. There are discussed most frequent non-RhD antibodies in the paper. Key words: alloimmunisation, non-RhD antibodies, prenatal diagnosis.


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Professor Marek Lubusky, MD, PhD, MHA

THE FETAL MEDICINE CENTRE
Department of Obstetrics and Gynecology
Palacky University Olomouc, Faculty of Medicine and Dentistry
University Hospital Olomouc
I. P. Pavlova 6, 77520 Olomouc, Czech Republic
Tel: +420 585 852 785
Mobil: +420 606 220 644
E-mail: marek@lubusky.com
Web: www.lubusky.com


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